F O R   P H Y S I C I A N S – resources
Recurrent Pregnancy Loss 
Introduction
Genetic Causes
Uterine Abnormalities
Endocrine Causes
Autoimmunity
Other Coagulation Abnormalities
Alloimmune Causes
Oocyte Abnormalities
Evaluation of Recurrent Pregnancy Loss
Treatment

Evaluation of Recurrent Pregnancy Loss
The evaluation of couples with two or more SABs should be directed toward those abnormalities, which have been proven to be causative:
 
Genetic:
  • Peripheral blood karyotyping of both partners
Uterine abnormalities:
  • Hysterosalpingogram
  • Pelvic ultrasound
Endocrine:
  • Luteal phase serum progesterone?
  • Endometrial biopsy?
Autoimmunity/Thromophilia:
  • Anticardiolipin antibody
  • APTT or RVVT
  • Factor V Leiden
Age:
  • Cyle day 2, 3, or 4 serum FSH and estradiol levels

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